Upstream Bio, Inc. — Key Metrics
2 years of history · ending 2025-12-31 · SEC EDGAR
Forensics
Three classic accounting-quality scores. F-Score (0-9, higher = better fundamentals); M-Score (>-1.78 flags possible manipulation); Z-Score (>2.99 = safe, <1.81 = distressed). Use together — single-score readings are noisy.
F-Score (Piotroski 0-9)
Z-Score (Altman; <1.81 = distress)
Per Share Metrics
Turnover & Efficiency Analysis (days)
Expense Ratios
Working Capital Analysis
Valuation Multiples
Enterprise Value Multiples
52-Week Range
Trailing Returns
ROIC vs WACC
Yields
Capital Deployment Yields
Liquidity & Leverage Ratios
Earnings Quality (OCF/NI · FCF/NI · Sloan Accruals)
EPS (Diluted)
$-3
Book Value Per Share
$6
Free Cash Flow Per Share
$-2
Cash Per Share
$2
Revenue Per Share
$0
OCF Per Share
$-2
Return on Equity
-35.4%
Return on Assets
-34.3%
Return on Invested Capital
-31.3%
Current Ratio
26.15
Quick Ratio
26.15
Asset Turnover
0.01
Days Sales Outstanding
85.43
R&D / Revenue
4793.5%
SBC / Revenue
362.0%
Capex / Revenue
5.8%
Working Capital
$338M
Net Current Asset Value
$338M
Invested Capital
$340M
OCF / Net Income
0.93
FCF / Net Income
0.93
Accruals Ratio (Sloan)
-2.9%
Net Debt
$-342M
Net Debt / EBITDA
2.13
Interest Coverage
-9.49
Cash Coverage
-7.89
Capex Coverage
-807.73
Tangible Common Equity
$340M
TCE / Total Assets
96.0%
Goodwill / Total Assets
0.0%
NOPAT
$-127M
Cash ROIC
-33.0%
WC / Revenue
11855.1%
Capex / D&A
0.88
Reinvestment Rate
0.0%
Asset Growth vs Revenue Growth
-47.0%
Stock Price (FY-end)
$27
Market Cap
$1.46B
P/S Ratio
512.30
P/B Ratio
4.30
P/TB Ratio
4.30
Enterprise Value
$1.12B
EV / Sales
392.64
FCF Yield
-9.1%
Shareholder Yield
-0.7%
R&D Yield
9.4%
Capex Yield
0.0%
Shares Variation (YoY)
293.6%
Beta (5Y)
1.15
Cost of Equity
10.3%
52W High
$30
52W Low
$6
Trailing Return 1Y
41.5%
F-Score (Piotroski)
2.00
Z-Score (Altman)
60.99
Earnings Forecasts
Per-quarter consensus estimates + actuals + beat/miss surprise. Sourced from Finnhub (Wall Street consensus aggregation).
Source caveat: Finnhub free tier returns the consensus mean only — analyst high / low / dispersion + analyst counts require a paid plan. A "$5.00 consensus" line above could mean "20 analysts at exactly $5" (high conviction) or "10 at $5.50, 10 at $4.50" (split). Treat single-line consensus accordingly.