Upstream Bio, Inc. — Earnings
Most recent reported period: FY2025 (Q4) (filed for period ending 2025-12-31) · sourced from SEC EDGAR
Next earnings (estimated): Wed, April 1, 2026 — 30 days overdue (likely already filed but EDGAR cache cold). Anchored to latest quarter-end + 91 days. Analyst-confirmed dates land in a follow-up wave.
YoY = vs same quarter prior year (seasonality-adjusted)
Recent earnings · last 8 quarters
| Quarter end | Revenue | YoY | Net Income | YoY | Op. Margin |
|---|---|---|---|---|---|
| 2025-12-31 | $668K | ↑+9.0% | — | — | — |
| 2025-09-30 | $683K | ↑+12.5% | $-34M | ↓-111.0% | -5539.4% |
| 2025-06-30 | $937K | ↑+83.7% | $-40M | ↓-172.3% | -4732.9% |
| 2025-03-31 | $566K | ↓-11.6% | $-27M | ↓-150.3% | -5656.0% |
| 2024-12-31 | $613K | ↑+36.2% | — | — | — |
| 2024-09-30 | $607K | ↓-2.3% | $-16M | ↓-415.5% | -3112.5% |
| 2024-06-30 | $510K | — | $-15M | ↓-477.9% | -3439.2% |
| 2024-03-31 | $640K | — | $-11M | ↓-255.8% | -2345.8% |
Analyst consensus estimates (EPS / Revenue) and implied move from options will land in a follow-up wave. For now, YoY-vs-prior-year-quarter is the surprise proxy.
Last earnings · FY2025 (Q4)
Revenue
$668K
↑+9.0% +$55K YoY
Earnings surprise · last 8 quarters
YoY % change · proxy for analyst surprise until estimates landEPS history · last 10 fiscal years
diluted, GAAP, annualNote: EPS reflects WEIGHTED-AVERAGE diluted shares for each fiscal year. Pre-stock- split values can blow up the early bars if SEC's XBRL data isn't split-adjusted — flagged as a known limitation; cumulative split-adjustment is a follow-up.
Go deeper
UPB Sankey — flow of dollars
See how revenue waterfalls through every line item to net income for the latest reported quarter, with prior-period comparison.
Open SankeyUPB Key Metrics — EPS, ROE, ROIC
10 CFA-grade fundamental ratios — EPS, BVPS, ROE, ROA, ROIC, Debt/Equity, Current Ratio. Compare across years.
Open Key Metrics